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Therapeutic
Expertise
ADVANCEMENTS IN
CENTRAL NERVOUS
SYSTEMS RESEARCH
For two decades, CRC has served as a dedicated partner in neuroscience drug development, concentrating exclusively on CNS programs to better support sponsors targeting the most complex therapeutic areas. That singular commitment has shaped a model built on scientific expertise, stable teams, and long-standing relationships with experienced investigative sites.
Specializing in neurology, psychiatry, and analgesia drug development, our team offers sponsors the depth and continuity needed to advance programs where precision, consistency, and informed guidance are paramount. CRC is more than a CRO—our team serves as your strategic partner in driving progress where complexity meets critical need.
200+
CNS CLINICAL TRIALS SUPPORTED
15
FDA APPROVALS SUPPORTED
81%
POSITIVE PHASE II TRIAL RESULTS (Out of 70+)
93%
POSITIVE PHASE III TRIAL RESULTS (Out of 30+)
Expertise In Action
CRC partners with sponsors across neurology indications including Alzheimer’s, Parkinson’s, multiple sclerosis, epilepsy, and rare neurological diseases. Our neurology specialists ensure accurate endpoints, reliable site engagement, and continuity across long-duration trials—driving clarity and confidence from start-up through submission.
Pain trials demand precision. CRC’s analgesia teams apply deep understanding of patient-reported outcomes, placebo control, and titration design to minimize variability and strengthen data quality. We’ve supported more than 15 analgesia trials spanning migraine, neuropathy, and chronic pain.
Psychiatry studies require sensitivity and scientific discipline. With experience in more than 55 psychiatry programs—including depression, schizophrenia, bipolar disorder, and anxiety—CRC delivers consistent results through embedded assessments, experienced raters, and robust patient-retention strategies.
Driving Breakthroughs
In Neuroscience
Our vision is simple: deliver a better CRO experience for those tackling the toughest challenges in neuroscience clinical research. Whether you’re designing a first-in-human study or executing a Phase III pivotal program, CRC offers the insight, consistency, and collaboration that drive success in CNS drug development.
Trusted Experience
In CNS Development
CNS trials demand a level of precision and continuity that goes beyond traditional development. Complex, often subjective endpoints, rater-driven outcomes, and vulnerable patient populations leave little room for error. Success requires anticipating operational risk early, maintaining consistency across long timelines, and understanding how clinical and site-level decisions influence signal clarity.
Our team is built for that reality. With deep neuroscience expertise, CRC approaches every study with discipline and foresight. Our team remains closely aligned with sites, fully engaged across the trial lifecycle, and applies structured processes that help reduce variability, ensure audit readiness, and protect signal quality.
From early-phase exploratory studies to pivotal programs, our team’s experience empowers sponsors with predictable timelines, high-quality data, and confidence in navigating the high-stakes environment of CNS clinical development.
Why Sponsors
Choose CRC
CRC combines scientific depth with operational excellence, ensuring that every study we touch produces accurate, actionable, and regulator-ready results.
Key Benefits:
- 20 years focused exclusively on supporting neuroscience clinical research
- Proven success advancing neurology, psychiatry, and pain programs from early phase through approval
- 86% employee retention supporting continuity, protocol familiarity, and consistent execution
- Embedded assessments expertise integrated with clinical, medical, and biometrics teams to protect data integrity
- Hands-on scientific and medical leadership guiding programs from IND strategy through regulatory review
- Long-standing partnerships with experienced CNS investigators and KOLs across 300+ sites for informed feasibility and durable site engagement
- Discipline, clarity, and operational rigor tailored to the demands of complex CNS clinical programs
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