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June 18, 2024

Why Include Cognitive Measures in a Trial Assessing Agitation Associated with Dementia?

A Systematic Review and Meta-Analysis of Agitation Trials in Individuals with Dementia


Randomized controlled trials have investigated the potential of various medications to treat agitation in dementia. Many such trials include measures of cognitive performance. It is unclear whether cognition is significantly impacted in these trials. The purpose of this review and meta-analysis was to determine the extent to which various agents used to treat agitation may impact cognitive performance in these trials.