Two decades of exclusively supporting bold CNS
clinical research shows up in the results.
About
Us
Built for Bold
CNS Clinical Research
Cognitive Research Corporation (CRC) is a specialized contract research organization (CRO) with an exclusive focus on supporting Phase I-III central nervous system (CNS) clinical research. Founded in 2006 and headquartered in St. Petersburg, Florida, CRC was built from the ground up around the complexity, nuances, and demands of neuroscience research. That singular focus, twenty years of doing one thing and doing it well, is what makes CRC different and what makes our team effective.
CRC was founded with a clear purpose: to deliver a better CRO experience for CNS. The pattern sponsors were navigating was clear: CROs that overpromised and underdelivered, that treated trials as transactional once the contract was signed, that didn’t have the scientific depth or the follow-through to back up what they sold, and that did not prioritize their people. Sponsors were left stepping in to do the job they thought their CRO would handle, managing gaps, solving problems, and constantly getting new team members up to speed.
Building that better experience required a team that genuinely cares and is relentless about delivering it. Sponsors are on a bold mission. They deserve a CRO that is a true partner, not a vendor, one that is equally committed to their success.
CRC is a team brought together by shared passion and determination, people who care deeply about transforming care for CNS disorders and who hold themselves to a higher standard. That is how CRC delivers a better CRO experience: approaching clinical research boldly, challenging the status quo, doing the work the right way, and showing up fully committed to every sponsor bold enough to take it on.
CNS Breakthroughs
Favor the Bold
Bold Research is the courageous pursuit of advancing CNS therapies by challenging the status quo, holding higher standards, and staying fully accountable to the mission.
At CRC, bold isn’t just what the team pursues. It’s how they pursue it: with discipline, precision, and a refusal to settle. Bold looks like deep preparation and proactive problem-solving. Ownership that doesn’t stop at the deliverable. A team that shows up every day fully committed to getting it right, not just getting it done. That is what makes outsourcing CNS clinical trials to CRC a fundamentally different experience.
A Better CRO Experience for Neuroscience
A True Partner, Not a Vendor
A vendor executes what you ask for. CRC is invested in the outcome. That means being proactive rather than reactive, bringing recommendations and solutions rather than status updates, and treating your mission as our own. Sponsors advancing CNS clinical research deserve a CRO that shows up as a true partner, not one that hands off responsibility once the contract is signed.
Embedded CNS Expertise
Every process, every tool, and every expert at CRC exists specifically to support Phase I-III neuroscience clinical trials. Sponsors and sites have immediate access to CRC’s medical and scientific leadership, every project team member specializes exclusively in CNS, and the in-house rater services team is deeply integrated with all functions to help protect endpoint quality from startup through closeout.
Continuity From Start to Finish
With an industry-high 86% employee retention rate, sponsors work with the same team from study start-up through closeout. No rebuilding relationships mid-study. No re-explaining the protocol to someone new. The people who know the program stay with it, and that continuity is a direct result of building a place where people want to stay and do this work.
Site Relationships That Hold
CRC maintains longstanding relationships with leading investigators and key opinion leaders across 300+ CNS-focused investigative sites, developed across hundreds of neuroscience clinical trials over twenty years. Strong site relationships drive accurate feasibility, faster start-up, and the kind of durable engagement that directly affects enrollment outcomes.
our impact
BY THE
NUMBERS
95%
NDA Approval Rate
(Across 20+ Submissions Supported)
77%
Positive Phase II Outcomes
(With 70+ Phase II Trials Supported)
73%
Positive Phase III Outcomes
(With 30+ Phase III Trials Supported)
our values
How CRC Works
Integrity
We uphold the highest ethical standards, ensuring transparency and honesty in all our actions and decisions.
Accountability
We own our commitments fully, delivering with diligence and responsibility at every step to ensure impactful, reliable results.
Respect
We actively listen and honor diverse perspectives, fostering a culture of collaboration that fuels innovation and elevates outcomes.
Collaboration
We combine our strengths and expertise, working seamlessly to overcome challenges and drive our shared vision forward.
Commitment
With resolve and determination, we transform obstacles into achievements that create meaningful, lasting change.
get in touch
Ready to Partner
With Us?
Back your innovations with 20 years of CNS expertise. Build your legacy boldly with CRC.
