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Analgesia
The CRO
for Analgesia
Pain trials present unique hurdles in drug development. Unlike conditions with clear biomarkers, pain is subjective, highly variable, and influenced by placebo and patient expectations. Designing studies that detect true analgesic signals requires specialized scales, careful endpoint selection, and experienced site investigators who understand the nuances of pain assessments and patient populations.
For two decades, CRC has been dedicated exclusively to neuroscience, bringing specialized expertise to pain research across chronic and acute indications. Sponsors choose CRC as their pain CRO partner because we know how to minimize variability, work hand in hand with experienced investigators, and deliver data strong enough to withstand regulatory review.
- Cancer Pain
- Migraine
- Neuropathy Disorders
- Pain Modeling
- Refractory Trigeminal Neuralgia
- Rheumatoid Arthritis & Osteoarthritis
HOW CRC DELIVERS
ANALGESIA TRIALS
Scientific Leadership With Real-World Pain Experience
CRC’s medical and scientific leaders have advanced pain therapies across mechanisms ranging from neuropathic to inflammatory pain. With decades of hands-on experience designing and executing analgesic studies, they anticipate challenges such as placebo response, titration schedules, and endpoint interpretation. This ensures protocols are both scientifically rigorous and feasible for patients and sites, giving sponsors confidence their data will stand up to review.
Consistent Teams Who Stay With Your Program
Pain studies require continuity. CRC’s employee retention rate of more than 86 percent means the same project teams stay engaged from start-up through closeout. That consistency preserves institutional knowledge, prevents delays from costly handoffs, and keeps progress aligned with your study goals.
Patient-Reported Outcomes and Compliance Strategies That Strengthen Analgesic Signals
Pain trials depend heavily on patient-reported outcomes like NRS, VAS, BPI, and WOMAC. CRC combines in-house rater expertise with proactive compliance strategies, including real-time ePRO monitoring and site support, to ensure patients record data consistently and on time. This approach reduces missing data, minimizes variability, and increases the reliability of analgesic endpoints.
Site Partnerships That Improve Recruitment and Retention
Pain patient populations can be difficult to identify and retain, particularly in chronic or neuropathic conditions. CRC’s long-standing relationships with investigators and pain research centers allow us to forecast enrollment accurately, identify practical recruitment pathways, and provide sites with the tools they need to keep patients engaged.
Proven Impact in
Analgesia Clinical Development
The proof is in our partnerships. 87% of our sponsors return for new collaborations – a reflection of the trust we build and the results we deliver.
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